The issue "Unable to setup WF RTMFP Notify Pipe" occurs when Lightroom CC is unable to initialize communication between the various Lightroom CC processes that run simultaneously on a user’s machine. Some users experience this issue when using a VPN because certain VPN services block all local network traffic that uses IPv6 (a type of internet protocol used by Lightroom CC for local process communication). Most VPNs can only route IPv4 network traffic, and so many VPNs disable IPv6 to ensure that no IPv6 traffic leaks out over your normal internet connection when you are connected to the VPN. Unfortunately, some VPNs have implemented this leak protection in such a way that it also erroneously blocks local network traffic that uses IPv6. This can prevent any app that uses IPv6 locally, even when not communicating with outside servers, from working properly. For users that encounter this issue and are using a VPN, there are two workarounds: Disable the VPN If it exists, then disable "IPv6 Leak Protection", or any similarly worded setting, in the VPN preferences. With this setting disabled, LrCC should work just fine. For users that are not using a VPN, it's likely that they have some other software installed that is preventing IPv6 network traffic. Likely candidates are firewall and anti-virus software. If you have such software installed, I'd advise you to disable it and then try launching LrCC. If this fixes the problem, then you will need to add some sort of exception to the anti-virus software for LrCC.
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