I went through the rounds on this issue with chat support. I will list the steps and also the chat session we had here: Steps: open activity monitor and close all Adobe related applications navigate to: /Library/Application support/Adobe In that directory you will see a folder named OOBE - Rename that folder to OOBEold Navigate to: MAC HD /Application/Utilities directory In there you will see a folder called "Adobe Application Manager" - delete it Download the Adobe Cleaner Tool from here: http://helpx.adobe.com/creative-suite/kb/cs5-cleaner-tool-installation-problems/_jcr_content/main-pars/accordion_container_1/accordion-par/accordion-item-1/accordion-item-par/procedure/proc_par/step_3/step_par/download/file.res/AdobeCreativeCloudCleanerTool.zip Open the Cleaner Tool and choose to clean "Creative Cloud" only. Download and install Creative Cloud again - https://ccmdls.adobe.com/AdobeProducts/KCCC/1/osx10/CreativeCloudInstaller.dmg Support Chat Session: Thank you for contacting Adobe. A representative will be with you shortly. You are now chatting with 'Soibam' Soibam: Hello. Welcome to Adobe Technical Support. Soibam: Hi Josiah, Josiah Wallingford: hello Soibam: I have received your query. Please allow me a moment to verify your account and to review the details of your request. Soibam: Thank you for staying online. Soibam: I understand that you are unable to update the Creative Cloud desktop application as you are getting error code 43. Is that correct? Josiah Wallingford: that is correct Soibam: Thank you for confirming the issue. I will be glad to check and help you with that. Soibam: May I know the exact error message you are getting while trying to update the product? Soibam: May I know the complete exact error message you are getting while trying to update the product?* Josiah Wallingford: I will have to run it again to get the error. One moment Soibam: Sure. Josiah Wallingford: Installing Update... 71% Installer was unable to access a critical file/directory. Please try installing again.(Error code: 43) Contact Customer Support Soibam: Thank you for the information. Soibam: Josiah, We will try performing some troubleshooting steps. Lets work together to resolve the issue. Josiah Wallingford: sounds good Soibam Soibam: Please quit the CC desktop application, close all Adobe processes from Activity monitor, re-launch it and try updating it. Josiah Wallingford: I already did that with the last tech... it gave us the same error Soibam: Please open Finder > Go > Utilities > Activity Monitor. Soibam: Okay. Josiah Wallingford: after we tried that we got disconnected Soibam: Thank you for the information Josiah Soibam: Please again close all Adobe applications including Creative Cloud desktop application from Activity monitor. Josiah Wallingford: okay Josiah Wallingford: okay done Soibam: Then, Rename Adobe Application Manager, OOBE folder. Soibam: Open Finder > Go > Go to Folder > type /Library > Application support > Adobe folder. Josiah Wallingford: okay Soibam: Please let me know if you have any difficulties in locating the folders. Josiah Wallingford: I found it Soibam: Great. Josiah Wallingford: now what? Soibam: Rename another OOBE folder Soibam: Navigate to Finder > Go > Go to Folder > type ~/Library > Application support > Adobe folder. Josiah Wallingford: I am in that folder. I see a folder in there called "OOBE". What would you like me to rename it to? Soibam: Rename OOBE to OOBEold. Soibam: Yes, you are correct. Josiah Wallingford: done Soibam: After that, Delete the Adobe application manager, Creative Cloud folder from MAC HD > Application > Utilities. Josiah Wallingford: done Soibam: Now, we will run Cleaner Tool. I will provide you the link to download the Cleaner Tool.. Soibam: Please click here. Soibam: Double-click AdobeCreativeCloudCleanerTool.zip to extract the Soibam: AdobeCreativeCloudCleanerTool.dmg. Josiah Wallingford: okay it is open... should I choose "Clean All"? Soibam: Please choose Creative Cloud only. Soibam: Please remove Creative Cloud desktop application and try installing the CC Desktop application. Josiah Wallingford: okay done Soibam: Now, try installing the CC Desktop application. Josiah Wallingford: Install it from where? Soibam: I will provide you the direct download link for CC Desktop Apps. Soibam: Please click here to download CC Desktop Apps. Josiah Wallingford: It is installing Soibam: Okay. Josiah Wallingford: okay it is installed... is that the latest version? Josiah Wallingford: its not asking me to update any longer Soibam: Please launch CC Desktop Apps and see if you are able to see CC 2014. Josiah Wallingford: I see them. They are wanting to be updated. Soibam: Please click on update. Josiah Wallingford: okay it is updating... looks like this will take a while Soibam: Okay. Josiah Wallingford: I will get back in touch if I have further issues. Soibam: Sure, I will keep the case open for your convenience so that you can contact us back if you still have the same issue. Josiah Wallingford: great. thank you Soibam: Your case number is ************ Soibam: You can refer to the case number to contact us back. Josiah Wallingford: Got it. Have a good day.
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