"Adobe Acrobat does not allow connection to" how to enable using registry

Getting the error: "Adobe Acrobat does not allow connection to" and I understand that this is a preference setting in Trust Manager.  I have tried working with the registry keys to try to make this work and I keep getting mixed results.  It is working on 1 machine and not the other, but the settings are the same. 

I have review the settings at:  https://www.adobe.com/devnet-docs/acrobatetk/tools/PrefRef/Windows/index.html

I modified the registry settings below:

• HKEY_LOCAL_MACHINE\SOFTWARE\Policies\Adobe\Acrobat Reader\DC\FeatureLockDown\cDefaultLaunchURLPerms\iURLPerms (make sure you choose update and NOT delete) from 1 to 2.  1= Block and 2=Allow.
• HKEY_LOCAL_MACHINE\SOFTWARE\Policies\Adobe\Acrobat Reader\DC\FeatureLockDown\cDefaultLaunchURLPerms\iunknownURLPerms (make sure you choose the correct on because they are 2 entries in different keys) from 3 to 2  (3=block and 2=Allow)

Please advise.