If the file is corrupt, it is caused by some failing component in the hardware chain.
That can be a failing drive or failing RAM, but it can also be camera/card/card reader/cables. Another possibility is the GPU, given that Denoise runs entirely in the GPU.
First of all, make backups, and don't do any critical work until you've narrowed it down.
Next try to replicate, and check the image carefully at every stage, to hopefully pinpoint it.
I think I may have figured it out, managed to reproduce it 3 times. I'm remote at the moment; working on a fiber connection over a VPN to my home network, with these images on my NAS. It's as fast as if I would be locally editing these images on my own network. However, it seems that saving the PSD to the NAS causes the corruption, if I save them locally it doesn't seem to be an issue. So seems like it's not a macbook related issue *fingers crossed*, more like a work-flow related issue.