Image completely disappears when in multiply mode

Hello! Never had this problem before - Trying to create mockups of shirts - multiply mode has always worked best for me, but recently when I try to put the layer in multiply the image completely disappears! ALl modes Multiply - Darker Color aren't showing the image at all. It's not just like a crappy blend it completely disappears - What's up with that? The image is a PNG, but I've also tried it as a JPEG - background picture a JPEG of the shirts and it's unlocked - Files in RGB mode. I'm at a loss!