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I had a previous version installed, and did a clean uninstall and updated to the newest version of Pro DC. These are the issues I've had thus far on a fully updated W10 system:
1) Printing to a printer does not work from within Adobe, but I can print pdf from inside Chrome. No error is reported, but the job is not sent to the Print Spooler.
2) "Check for Updates" results in an error "An unimplemented or obsolete function was called."
3) "Repair Installation" results in a few minutes of a taskbar, which closes with no reports or errors on screen.
4) When I attempt to sign a pdf (one which I was able to sign via online Adobe Reader) with the "Draw yourself" option, an empty pop-out window appears and nothing happens.
Hope you are doing well and sorry for the trouble and the delay in response.
Please check out the correct answer marked in the similar discussion https://community.adobe.com/t5/acrobat/menus-non-responsive-or-generate-an-error-message/m-p/1230605... and see if that works for you.
Following a clean install of Adobe, the rather large W10 update, and a second install, the issue seems to be resolved. Thanks!