We are currently using Adobe Acrobat DC (22.001.20169) and have run into an issue that we did not have in prior versions of Adobe. We have an application that passes a filename as a command line parameter to adobe.exe. With this version, when the file name contains spaces we receive an error "There was an error opening this document. This file cannot be found". I was able to reproduce this by opening a command prompt, navigating to the directory where the adobe Acrobat.exe resides and issuing a command such as
acrobat.exe c:\temp\file name with space.pdf
Acrobat then loads and displays the error in a dialog.