I have a user that when he opens some forms now that the data is already populated using a previous form's info. Autofill is turned off in Preferences. I removed his previous install, ran the Adobe cleaner, and installed DC Pro with the same problem. I assume the forms are fine since they open on other computers ok and they look ok in Edge. He's only recently having this issue. I'm not sure if there's a setting I need to check or if I should just blow out his Win10 profile.
You can't compare viewing a PDF in Edge with viewing in Acrobat. Edge doesn't support all things that are possible with PDFs. There may be running a script in the form to populate the data for example. Can you share the particular form?