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Error opening Adobe attachments from Outlook

New Here ,
Sep 19, 2025 Sep 19, 2025

When opening Adobe attachments from Outlook I frequently get the error pop up "The instruction at 0x00007ffce23bed7d referenced memory at 0x0000000000000018. The memory could not be read" It does not stop me from opening the attachment I hit ok and the pdf opens, its just annoying. I have uninstalled run the Adobe cleaner reinstalled. I have turned off protected mode. I have cleared my cache, dumped my temp folder. Any other ideas?

 

Thanks

TOPICS
General troubleshooting , How to , PDF
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Adobe Employee ,
Sep 19, 2025 Sep 19, 2025

Hi ginger_0574,

 

Thank you for reaching out, and sorry about the trouble caused.

 

This is a known issue, and the team is working on the fix. We will let you know once the fix patch is available.

Please share details of your current Acrobat and OS version. 

 

In the meantime, please try the workaround mentioned below:

- Right-click on your Adobe application icon and select Properties.

- Select the Compatibility tab.

- Click on Run Compatibility Troubleshooter.

- Select Try Recommended Settings.

Check if that helps.

 

We appreciate your patience.

 

Thanks,

Meenakshi

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Adobe Employee ,
Sep 25, 2025 Sep 25, 2025

Hello,

 

Hope you are doing well. 

 

We are live with a new update (25.1.20744) that fixes this issue. Please update the app to the latest version and let us know if the issue is fixed for you.

To check for updates, go to Menu > Help > Check for Updates.

 

To know more: https://adobe.ly/46VbRYI


Regards,
Souvik.

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New Here ,
Sep 25, 2025 Sep 25, 2025

Hi, just to add to this issue, we've been experiencing the same thing recently.

 

We updated our users to the latest version (25.1.20744) but at least one of them has had the issue happen since.

 

As far as I know, before the update most PDFs were being created and opened directly by our ERP system but there were also probably some opened through Outlook.

 

The most recent crash, after the update, came from a PDF opened through Outlook.

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New Here ,
Sep 25, 2025 Sep 25, 2025
LATEST

Just to add to my previous comment, in case it might help with troubleshooting, the issue happened to another user since the newest update.

 

If protected mode is turned ON (Menu => Preferences => security(enhanced) => protected mode at startup), then Acrobat freezes completely when they either try to save a signed document or when simply trying to open a PDF by doing "Ctrl + O" or "Menu => Open", the file explorer window didn't seem to show up.

 

We had to re-disable "Protected mode at startup" which is definitely not ideal long term.

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