As the option for "Two-sided" if greyed out in the Print window, please make sure that your printer has the dual side printing capabilities.
Also, make sure that the box for "Duplex Unit" in the printer settings is checked.
To check that, go to Settings > Printers & Scanners. Select the printer you are using from the list of printers available.
Then click on "Options & Supplies" tab at left in that window and go to "Options" tab.
Check the if the box for "Duplex unit" is marked or not.
If it is not checked, check the box and click OK at the bottom to save the settings.
Then try to print the PDF and check if you able to print on both sides or not.
Hope this helps.
Let us know how it goes.
I just recently developed the same problem. First, my printer was jamming excessively because it could not print double sided. Since it was an older printer, I saw its imminent death, so I instantly bought a new printer. After installing the new printer, everything printed from Adobe DC came out double sided. Since this was my first print job, I assumed the printer was the problem. I configured the printer to print single sided but the problem continued. That's when I noticed that the "print on both sides of paper" was checked in adobe. I unchecked it but the problem never went away. Each time I returned to the print menu, the option was still checked. I printed each sheet page by page from adobe on my new printer as well as the old printer. Each printed fine. I also printed from other applications and all was good. My conclusion is, the double-sided option in adobe reader cannot be changed. It appears that after each de-select, the option automatically re-selects the option when you initiate the print action. This is because every time I go back to the print menu, the option remains checked even though I deselected it in the previous print job. Wish I could have said all these in fewer words. Thanks.
Sorry to say that there is no option to change the default settings of the Print window in the application.
That is the reason the option is selected by default. You need to manually de-select the option.
This is an as designed behavior.
You can add your feedback for this over here Feature Request/Bug Report Form.
Let us know if you need any help
Thank you for responding to my comment. Just to emphasize, the default settings cannot be manually changed. As I stated, each time I manually de-select the option, the print job comes out double-sided. Essentially, manually de-selecting the option does not work. It is behaving as if it was greyed out. I am not saying it is greyed out, it is just behaving like that.
Sorry as I misunderstood the issue.
Please make sure that the application is updated to the latest version available.
Refer this link Release Notes | Adobe Acrobat, Reader to check the updates available.
Ty once to reset the application preferences. Take help of the steps mentioned here How to reset Acrobat Preference settings to default.
Also, reboot the device once.
Check if that helps.
Could you please let us know the application version number currently installed on your Mac?
To check that, take help of the steps mentioned here Identify the product and its version for Acrobat and Reader DC.
Did you recently make any changes after which you start experiencing the issue?
Let us know if the issue still occurs.
I am experiencing the same problem with Adobe Acrobat Reader DC Continuous Release 2019.021.20056. The Print on Both Sides is grayed out yet when I print PDFs from Google Chrome I can print double sided with my Brother MFC-9560CDW. I can also print double-sided from Word or Excel. Please help with Reader DC!