Enable global object security policy - Check box won't remain unchecked

[wlynn.iam]

When attempting to uncheck the "Enable global object security policy" option under Preferences>JavaScript, occasionally the box won't remain unchecked. So I'll go in, uncheck the box, close Preferences, then go right back into Preferences>JavaScript and the box will be checked again. Any idea what's going on here, and what to do about it?

Update: No settings under Preferences will save when I make changes. None of the checkboxes remain checked/unchecked after I close Preferences and return to it. I uninstalled and reinstalled Reader also, no change.

[try67]

Version of Acrobat? OS version?

[wlynn.iam]

Most current version. Windows 10 up to date.

[Thom Parker]

Why do you need to remove global object security? Maybe there is anoter way to accomplish the required functionality?

[wlynn.iam]

Vitrium security on pdfs. There might be another way but I want a solution to this problem, not the fact that the security is in place. This works when Reader isn't being buggy.

[Thom Parker]

If it is the case that no settings are being saved, then Acrobat is not closing properly. 

The first thing to do is to check the task manager after Acrobat closes to see if it is running in the backgound, or if there are multiple background instances. 

If these exist, kill them. 

There are several possible culprits for this problem. The Acrobat install could be damaged, or one of the settings files or feature components could be damaged. Doing an Acrobat Repair could fix this.   

The cuprit could be a 3rd party plug-in. If you use any of these, move them out of the plug-ins folder (or uninstall), then test to see if the issue persists.

[wlynn.iam]

I checked it both those first two options already. I'll check on the plug-ins. Thanks.