Hello, we are having very similar issue, The apps are deployed for teh entire organization adn from a group of about 80-90 users at the moment 10 to 15 (that we know) are having this problem. 60 of the users are current DC Pro paying licenses.
We've tried adding and removing the users and nothing changes. Opened a ticket with Microsof Premier and Microsoft pointed us to this thread adn Adobe Support.
We can open the a file on the Same computer in a different browser session with one user but not with one of the users affected. Always tryign the same exact files, Once this error occurs no PDF files will open in the Adobe Cloud, as soon as this error shows up once in one file ti is broken for all the user PDF files in SharePoint.
There's a similar thread that is almost identical to our problem.
https://community.adobe.com/t5/adobe-acrobat-online-discussions/unable-to-open-pdfs-in-sharepoint-on...
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