Was excited to install 2022 version of AME, but it has proved ultimately useless.
It constantly loses connection with After Effects. Folks in our department may get 2-3 renders before it stops receiving new renders in the queue. The only way that has worked for me to fix this is a full restart of the system
Additionally, even when it does receive new renders, I'd say about 80% of the time, they hang and fail within seconds to the point that AME needs to be "Force Quit" to restart the application. The only "renders" that seem to work with 2022 are converting existing video. I have to render everything in After Effects and then down-convert in AME once I have a rendered file, which pretty much makes AME useless in the end.
I've just uninstalled 2022 and put 15.4 back on my system. Hopefully that works.
For the record, I've tried cleaning the cache in bot AE and AME to resolve this and nothing has changed.