I have a weird bug with the color picker. I have a MacBook pro mid-2017, and this bug is only happening with my external display (Philips 4k phl 288e2). Basically, if I have an element with a certain color, and I use the color picker the pick its color and apply it to another element, the result is not the same color. I'll get a less saturated color with less saturation. if I move adobe xd to my MacBook display, it is fine. I only get this bug with my external display.
We are sorry for the delay in response. Would you mind sharing the screenshot of your about XD info page? Have you tried signing out of XD and Creative Cloud app, restart the machine and then sign back in? Is it happening with every file or with a specific file? Please check if any antivirus is causing the issue.
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Info about XD can be seen clicking the XD next to the Apple icon at top left and selecting the About XD option. Hope this helps!