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The home page is empty and I cannot create a new file. I have uninstalled the XD and Creative Cloud and reinstalled them more than 50 times for all sorts of little problems of XD.
I solved it myself right after I post it. I share the tip with you.
My system is MacOS Catalina 10.15.5
Inside /Users/username/Library/Application Support/Adobe
There's a folder "Adobe XD". Delete it.
And restart the software.