Absurd error while opening Adobe AE

[alessandro22718261lk2r]

Whenever I try to open After Effects it says "after effects warning: the directory 'E:' could not be created. please check the parent directory protection or permission rights.

The most absurd thing is that I don't get why or where After Effects would even try to create a folder called as my HDD (I have it installed on my SSD) 

Tried to run as an administrator several time and gave permission to a bunch of folders but it still won't work.

I'd really appreciate if you could help me.

[Mylenium]

Without any system info and other technical details we can't tell you much. AE even attempting to do such a thing could point to issues with your drive naming and letters, so start by having an excursion to your sisk management system control. A screenshot of that certainly wouldn't hurt. anyway, we seriously need more info.

Mylenium