In theory probably yes, but in practice it's unlikely. You'd have to monitor a ton of ports and connections, figure out the shared cache handling and temp files and on top of it it would all be hyper sensitive to the slightest network timing issues. A single missed frame/ packet and everything stops. Also of course you would still have to ensure the actual install is in place, all plug-ins work, all fonts are synced and so on. I don't think it's feasible on any rational level and if it is, at least the amount of work and resources needed to keep it running will multiply.
It occurred to me there will also be quite the hit to bandwidth as the artifacts (Video and audio clips, imagery etc.) would have to transport through the network for every video … and there are many.
Sounds like a big no.
Your point re resources required would kill it right there. I want this thing to run - more or less - 'unattended' but if it’s held together with duct-tape and binder-twine … that’s unlikely.
I don’t have the appetite to set up a big render farm, so to prepare for growth, I need to investigate cloud based comping and rendering. I’ve read that AE can be hosted on AWS, not sure about AME. Then again, with the juice available on AWS, perhaps I can just have AE do the comping AND rendering.