I have been having this issue (which has been going on for years now) where my Wacom tablet/pen stops working when I use AE. The issue does not happen right away, sometimes it happens within minutes after I launch and use AE and sometimes it may take up to hours. What happens is the mouse/cursor does not move when I am hovering over the tablet. The only way for it to move is when the pen is putting pressure on the tablet and I drag, in which case also makes it click AND drag at the same time. This ONLY happens with After Effects and it's ONLY the Wacom that stops working, when I switch to a mouse it works fine. The only way to fix this issue is to restart the computer which is only a temporary fix.
Please help! Wacom and Adobe "specialists" were not able to resolve this issue for me.
Error or problem, Performance, User interface or workspaces