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I wonder why I can't open After Effects?
This error appears!!!!
Without any system information we can't really tell you anything. For all intents and purposes "Unknown" means what it says and without a bit of context even we can't guess.
Sorry for the crash issue with After Effects. As Mylenium mentioned, we'd need more information to troubleshoot this issue properly.
Try validating and removing the faulty fonts using Font Book: https://support.apple.com/en-in/guide/font-book/fntbk1000/mac
Let us know how it goes.