I think this is a bug in 3.3.1. I wanted to check if anyone else was seeing it.
I have multiple audio interfaces on my system. When Character Animator is linked from an AE or Premiere project, I often see this message "The device has changed and no output channels are present..."
When I have left a project rendering, I often come back to maybe ten instances of this screen. It makes no difference if I tick the Don't Show Me Again box. I have tried changing my default system audio. It is only Character Animator and none of the other Adobe apps are throwing up this message. I am used to seeing this message in other CC apps if I unplug my USB Audio Interface - which makes perfect sense - but there's nothing like that going on.