The Platform Support Doc says MySQL 5.7. I'm not sure what that means. So, I'll try a different approach.
Is anybody successfully running ColdFusion 2016 and MySQL 5.6?
It means exactly what it says on the tin: ColdFusion 2016 supports MySQL 5.7. But I can assure you I have been running ColdFusion 2016 together with MySQL 5.6.10 successfully for several years now.
ColdFusion 2016 works just fine with MySQL 5.6. You will need to supply your own connectors from MySQL (MySQL :: MySQL Connectors ). Download the "JDBC Driver for MySQL" and copy the .jar file into the ../lib folder. If you are running Standard edition the path is ./ColdFusion2016/cfusion/lib/ for most installations. For Enterprise version especially if you have multiple instances each instance that access MySQL will need the connector. The path would be ./ColdFusion2016/[instance name]/lib/.