"Seeking settings cf 2016 to generate a PDF with CMYK." (Translation)
Are you attempting to use CFDocument to "generate a PDF using CMYK images" or "generate a CMYK PDF with an ICC color profile"?
If you are attempting to use non-RGB images, CFDocument's PDF generation will be really slow and may render the images properly.
The work around that we've been using (and produces reliable, consistent results with CF8, 9, 10, 11 & 2016) is to use GraphicsMagick (opensource) to convert image color profiles to RGB (ColdFusion may throw an error depending on the source image) and then use WKHTMLTOPDF (opensource) to convert the HTML to PDF.