Same here (on macOS): I enjoy using the Creative Cloud apps (Illustrator, Acrobat, etc.) but I am not interested by the cloud itself. I thought I had found the combination of preferences in the Creative Cloud app (and in System Prefs > Extensions) to prevent the Creative Cloud Files folder from recreating itself automatically, but no: every time I delete this (empty) folder, it's back the next time my Mac is restarted. That's really annoying. With Office 365, for example, once you set the OneDrive app such that the OneDrive folder is not created, it stays like that until you change the setting.