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Unable to open EPUB with Adobe Digital Editions

New Here ,
Dec 18, 2016 Dec 18, 2016

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I have the latest Adobe Digital Editions installed on my Windows 10 but when I try to open an ebook in EPUB from the library it won't open and I get a message saying:

"This file does not have a program associated with it for performing this action.  Please install a program or, if one is already installed, create an association in the Default Programs control panel."

What do I do?

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LEGEND ,
Dec 19, 2016 Dec 19, 2016

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Right Click on the epub file.

Choose open with.

Choose Digital Edition.

Activate the option that it was allways with the programm.

Then is should work.

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New Here ,
Dec 19, 2016 Dec 19, 2016

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Thank you for your reply.  Unfortunately this doesn't seem to work.  When I try to open with the choice of Digital Edition and small box appears with the words "Error! Check Activation".

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LEGEND ,
Dec 19, 2016 Dec 19, 2016

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Close all applications.

Choose Start > Run.

In the Open text box, type regedit and then press Enter. The Registry Editor opens.

In the left pane of the Registry Editor, locate the following registry key: HKEY_CURRENT_USER\Software\Adobe\Adept

Right-click the Adept key and choose Delete.

In the Confirm Key Delete dialog, click OK.

Close the Registry Editor.

Open Adobe Digital Editions and reauthorize.

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Explorer ,
Mar 30, 2018 Mar 30, 2018

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I also cannot open an epub Indesign file in Digital Editions unless I export as a 2.0 epub.

I have ADE 4.57 and 2018 InDesign CC.  I/ trying to create an epub for a 335-page book.

Need to find errors, etc and I must have a 3.0 file. Does the Registry correction work for this

problem?  

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Community Beginner ,
Aug 12, 2018 Aug 12, 2018

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The "Open With" right click doesn't work

The "regedit" operation doesn't work after I've reauthorised the computer

Uninstall and reinstall doesn't work

Ordering paper version of the book now

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New Here ,
Jun 22, 2019 Jun 22, 2019

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I cannot open them on my copy either.  It says my ADE is 4.5.10.  It took me forever and a few forums all over to figure out how to open the ADE program.  Now I am getting errors GALORE trying to read the item.(s)

Tried saving my folder as My Digital Editions.old

(lets me run the program at least)

I also get these errors:

Error getting license (when I have received a copy from Netgalley or the publisher for an ARC).

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