I have no such problems with latest Creative Cloud apps.
Which Adobe Apps and versions are you using? And which version of Windows?
Legacy Creative Suite is NOT Hi-DPI aware and it never will be because it's discontinued & unsupported software.
OPTION 1: Reduce your display's screen resolution at the OS level
OPTION 2: Increase text & icon scale to 125-150%. This may have other consequences however, such as truncated panels.
OPTION 3: Use Windows Magnifier (Win key + plus sign) to facilitate easier viewing at normal resolution & scale.
Hope that helps.
Nancy O'Shea, Product User & Community Expert
Alt-Web Design & Publishing ~ Web : Print : Graphics : Media