I, too, have a new MacBook Pro, with the root volume formatted as case-sensitive. This is an OS option, and required for my work. I can easily create a case-insensitive volume specifically for (apparently Antiquated) Adobe Acrobat DC / Creative Cloud and did so. But the installer insists that the boot/root volume must also be so formatted.
This is unacceptable. This is not a feature of your software, this is a bug, which prevents paying customers from installing your software, requiring that they modify their systems to even attempt do so. That lack of compatibility with a years-old standard should not be tolerated by the Software Engineering management.
I was an Adobe software engineer following their acquisition of Frame Technology in 1996 through 2010. I proudly worked on server-side enterprise products as well being on the team that first stood-up Acrobat.com and on Acrobat plug-ins in the Adobe Advanced Technology Labs. In my tenure I worked on Builds, Release and Installers. This incompatibility would never have been tolerated in my tenure. What has happened, Adobe?
I am obliged to cancel my subscriptions as YOU have made YOUR software UNUSABLE to someone who WANTS TO PAY YOU.
It is a major undertaking to rewrite the applications to support a case-sensitive file system, so please make sure to include complete information on why you are unable to use a non-case sensitive file system. Any details such as applications or services that require this configuration would be appreciated.