HOW TO UNINSTALL ADOBE FLASH AND ADOBE READER FROM WINDOWS 10
Like everything else, with Control Panel.
For Flash Player, you can use the standalone uninstaller posted at https://helpx.adobe.com/flash-player/kb/uninstall-flash-player-windows.html
Note that the uninstaller will not uninstall embeded versions of Flash Player.
Google embeds Flash Player PPAPI in Chrome and Microsoft embeds Flash Player ActiveX Control for IE/Edge in Windows 10. The uninstaller will not remove theses embeded versions. It will only uninstall Flash Player versions intalled manually by you.
For Acrobat Reader, see https://helpx.adobe.com/acrobat/kb/uninstall-reinstall.html or post to the Acrobat Reader forum for assistance.