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The big blue X shows that it is an image (look in the Links panel).
Don't open a PDF in Illustrator (unless it was saved with Illustrator capabilities option).
Use the original Illustrator .ai file to edit the content.
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What did you do? Open a multipage PDF?
If that is the case you could try if embedding all the pages helps. But still you won't have a lot of joy editing it.
Did you save the file on a server?
Did Illustrator crash?
And what Ton wrote.