Your computer going to sleep should not change any of the values of the fills in your file. If you were using colors in document 1, opened document 2 with the same exact color swatch names, copied and pasted that in document 1, the colors would shift if they were defined differently.
Bridge >> Edit >> Color Settings. Make sure all your adobe apps are set to the correct color management.
Might be a tech issue with the recent update, as seen a similar post about color looking like CMYK versions. Quit and restart illustrator. Try toggling view >> pixel preview to force the redraw or CTRl Y for view outline mode.