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Error -54 in Illustrator CC 2017

New Here ,
Jun 16, 2017

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Hi,

I'm getting an error message when I start up Illustrator that says: "Can't open the illustration. The file is locked or in use."  ID:-54 (pictured below)

Someone please help! I've already uninstalled and reinstalled several times.

Screen Shot 2017-06-16 at 9.34.49 PM.png

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Error -54 in Illustrator CC 2017

New Here ,
Jun 16, 2017

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Hi,

I'm getting an error message when I start up Illustrator that says: "Can't open the illustration. The file is locked or in use."  ID:-54 (pictured below)

Someone please help! I've already uninstalled and reinstalled several times.

Screen Shot 2017-06-16 at 9.34.49 PM.png

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Jun 16, 2017 0
Adobe Community Professional ,
Jun 17, 2017

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Is the file on your harddisk? Or on a server?

If on a server: download it to your harddisk first, then open.

If on your harddisk: check access privileges.

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Jun 17, 2017 0
New Here ,
Dec 19, 2019

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Hello I got the same message and the file is on hard disk 

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Dec 19, 2019 0
Community Beginner ,
Dec 18, 2017

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I updated to Illustrator CC2018 and get the same message when I launch the program and try to make a new document.  It makes no sense. Here is what I see every time.  Can anyone please help?

Screen Shot 2017-12-18 at 3.16.59 PM.png

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Dec 18, 2017 0
Adobe Community Professional ,
Dec 18, 2017

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So this is High Sierra? Is it updated to the latest version?

Which file system?

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Dec 18, 2017 0
Community Beginner ,
Dec 18, 2017

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I am on Sierra.  I usually wait just a little before I update my operating system to get the bugs fixed.

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Dec 18, 2017 0
Adobe Community Professional ,
Dec 18, 2017

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julietc30864518  schrieb

I am on Sierra.  I usually wait just a little before I update my operating system to get the bugs fixed.

That's good.

When did you last restart the computer?

Are any third party plugins installed?

Is a printer connected and turned on?

Can you try and rebuild the preferences?

Rename the folder so that you can revert in case it doesn't help:

How to set preferences in Illustrator

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Dec 18, 2017 0
Community Beginner ,
Jun 24, 2020

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June 2020 and this issue is still very much prevelant. I have just bought a new MacBook and have installed illustrator and I am trying to open my work from OneDrive and it gives me this error. 
error -54

why am I paying adobe money?? 

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Jun 24, 2020 1
Adobe Community Professional ,
Jun 24, 2020

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What happens when you move the file to the local harddrive?

Also: is a printer installed, set up as default printer and turned on? If not, install a PDF printer.

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Jun 24, 2020 1
Community Beginner ,
Jul 14, 2020

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For me, the issue was Dropbox smart sync. After CTRL clicking the containing folder and selecting "Smart Sync>Local", I was then able to open the file in illustrator 2020

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Jul 14, 2020 1