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Hi all,
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Sounds like the OS isn't responding rather than InDesign.
I don't know if this helps you
https://apple.stackexchange.com/questions/408063/big-sur-unable-to-focus-any-app-or-make-mouse-keybo...
It seems to be related to the Touch ID sensor.
Or I'm wondering now if it's something to do with InDesign Preferences>Interface
Maybe turn off Enable MutliTouch Gestures
And see if setting the UI scaling to small or large makes a differences.
For InDesign you could try
There's a few fixes you could try that I have saved for situations like this
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Try resetting your preferences:
The easiest way to reset everything is to delete the InDesign preferences: as soon as InDesign starts to boot hold down Shift, Alt, Ctrl (and Apple/Cmd if working on a Macintosh). A dialog will appear asking to delete the InDesign Preferences, select 'Yes' on this dialog.
Further info and instructions here if needed:
https://helpx.adobe.com/in/indesign/kb/indesign-preferences-support-file-locations.html
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Reinstalling rarely fixes everything - you can do a complete reinstall using the
Creative Cloud Cleaner Tool https://helpx.adobe.com/creative-cloud/kb/cc-cleaner-tool-installation-problems.html
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Try turning off the GPU Performance in the InDesign settings.
See if that helps
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Have you updated to 17.1? I don't know if that will fix it but it's worth a try.