I also do not have promlembs with this. It could be a hardware problem or some other utility in your operating system that has a conflict. What operating system are you using, have you tried swapping to a different/external mouse? Does the mouse you have need a driver/driver uppdate.
Untill you find the problem perhapps you could work around it. A usefull shortcut is cmd/ctrl-0 (zero) ro zoom out to fit page/artbaord in window add alt/option (ctrl/cmd-alt/opt-0) to fit spread/all artboards.