InDesign 2021 becomes unresponsive after launch

[#1]

InDesign 16 has become unresponsive when I attempt to launch it. Yesterday it was working just fine. I am on a MacPro running Catalina. All apps and upgrades are applied to adobe software and the Mac.

I attempted to remove any preference settings to no avail. I then completely removed InDesign and all preference files that I could find associated with it. I restarted my computer and then reinstalled InDesign. The issue did not go away once I finished installation.

I am not sure how this can still be an issue when I removed everything related to InDesign and started from scratch. Is there a preference file that is somehow synced with Creative Cloud that gets downloaded when the software is installed? If so, I don't know how to turn that off.

Any other insights would be helpful as I had this issue happen on another mac in our building earlier this year and an Adobe tech had to spend over an hour remoted into it and messing with files and settings before the software would work again.

I'll add another wrinkle here...Illustrator is acting the same way but Photoshop is just fine.

[#2]

InDesign 16 has become unresponsive when I attempt to launch it. Yesterday it was working just fine. I am on a MacPro running Catalina. All apps and upgrades are applied to adobe software and the Mac.

I attempted to remove any preference settings to no avail. I then completely removed InDesign and all preference files that I could find associated with it. I restarted my computer and then reinstalled InDesign. The issue did not go away once I finished installation.

I am not sure how this can still be an issue when I removed everything related to InDesign and started from scratch. Is there a preference file that is somehow synced with Creative Cloud that gets downloaded when the software is installed? If so, I don't know how to turn that off.

Any other insights would be helpful as I had this issue happen on another mac in our building earlier this year and an Adobe tech had to spend over an hour remoted into it and messing with files and settings before the software would work again.

I'll add another wrinkle here...Illustrator is acting the same way but Photoshop is just fine.

[#3 · Accepted solution]

There is a point upgrade to InDesign just launched.

Have you plenty of RAM and spare disk capacity?

Consider uninstalling InDesign, using the drop-down menu in the Creative Cloud app and then running Adobe Cleaner -- https://helpx.adobe.com/uk/creative-cloud/kb/cc-cleaner-tool-installation-problems.html