Solved it. I am running an application called "Webroot Secure"; if I select "Pause Secure Keyboard Entry" then it solved this.
Thanks for letting us know how you solved it.
Adobe should f**king stop blaming other programs. Just f**king fix the bug! If illustrator has no problem at the same time when InDesign becomes absolutely useless (with broken option and shift key) then there is no excuse to blaming on other programs. It is clearly an Indesign problem. Stop keep tell your paid user to find walk around, relaunch and reboot every time the stupid bug appear. Fix you sh*t Adobe!!!
Thank you for letting us know how you solved it! This bug only affects Indd, Illustrator has no issues with me running Webroot Secure. Now I'm kind of worry that every update, something else will come up. Hope Adobe can fix this for future updates.
I forgot to mention that I am a mac user. Not sure if this happens for windows users.