When converting from a LR3 catalog, as well as when switching back manually to PV 2010, the new noise sliders ("Details" for luminance and color, as well as "Contrast" for luminance) are not active and cannot be changed.
I have no idea if just the sliders are disabled or the associated development settings vanished, too (as it is the case for the tone curve).
LR4.0 64 Bit, Win7, tested with a RAW file from Canon 40D.