The vast majority of the world wide Adobe customer base has computers be they laptop/notebook or desktops with both Descrete GPUs and integrated video controll. Only a few have just integrated (old laptops, ancient desktops). And extremely few have any issues with that. Normally Photoshop, Lightroom, and Lightroom Classic ignore the integrated video controll.
For both laptops/notebooks and desktops the integrated video control is on the motherboard. Laptop/notebooks have the GPU on the motherboard as well, desktops on an add on card. All in ones like IMacs a bit different.
Normaly you do not have to accomplish any tweaking.
As for Dual Graphics cards, that issue is all about Descerte Graphics cards. This is usually something hard core gamers have, but normally they have two absolutly identical cards connected together. Problems would occur if the two cards had different drivers (as such probably different cards)
Will try to follow with some Adobe links