If you re-select the same (or equivalent) images as were used initially when creating the preset, and make sure those aspects of processing that you want to vary by ISO are suitably varied, you can right-click on the preset and choose to update that.
A dialog window appears the same as before, where you can check the aspects of images' processing that should be affected by this preset when it's used in future, and un-check those aspects that it should leave alone. It will probably be necessary to re-select here, that the updated preset should remain iso-adaptive.
The same as before, the highlighted images are then analysed (from scratch, afresh) and any adjustment differences found between them, are presumed to be intentional variation based on ISO.
If you do not explicitly choose "iso-adaptive" again when updating, AFAICT this preset will revert to being a conventional one. It would only grab current processing from the most-selected (active) image, disregarding any other images that were highlighted also. And its action would thereafter disregard ISO, so far as the images it was used on.