That isn't a great user experience an Lightroom desktop is giving an error message "unable to create directory" while trying to upload images, we're sorry to hear about this. Let us help make it right.
You likely still have a permission issue at the drive or folder level. You will need to use the Mac OS/Windows to change the permissions for your User Account for that (and perhaps other) locations. If changing doesn't work you may need to repair your permissions.