No, that is not really possible. The reason is that there is a huge difference between how Lightroom works and how Photoshop works. Photoshop changes pixels, so it can change a single pixel, regardless of the other pixels around that pixel. Lightroom is a non-destructive editor, and often works with raw files. It does not change pixels, but stores a 'to do list' with the changes. If it works on a raw file, the pixels surrounding a single pixel do have an infuence on that single pixel, because of the 'demosaicing' that needs to be done on the raw data. That means that Lightroom does not have the luxury to change an individual pixel regardless of the surrounding pixels. The only way that Lightroom can do true content-aware fill is when it creates a new file in the process. That is why true content-aware fill is now available in panorama merge (where a new DNG is created), but not in spot healing.
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