Hi, 100% opaque means 0% transparent. If that is what you mean, yes, it is possible, and such patterns exist in the legacy set you can get from the local menu of the patterns panel.
if you meant 100% transparent, I do not think it is possible. When you erase to 0% opacity, color info is lost (I feature request a preference switch for that, but it might be gone)
you might be able to save a very low opacity pattern, then lower its opacity again from the layer styles, or from the layers opacity. But I wonder what you would do with o% opacity pattern. You can also adjust the colors of the transparency grid in the preferences.