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I have a PC (Win 7-64 Pro) with 64 GB RAM and I am getting an error message that says "Could not apply the workspace because there is not enough memory (RAM)". I am trying to open a large 32-bit TIFF File (~810,000 KB). My C-drive is tight on space (~7 GB Free) but I have tons of space on othter drives specified as scratch disks. With 64 GB of RAM I cannot understand why this error pops up.
Help...
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If your C: disk is Photoshop's first scratch disk Photoshop will fill your C: disk in short order and you systems performance will go to pot make sure C: is not Photoshop first scratch disk. Your Performance should not look like this

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Hi here are some responses to some of the comments above:
Here is what I am running:
Adobe Photoshop Version: 19.1.6 20180808.r.398 2018/08/08: 1185588 x64
Number of Launches: 56
Operating System: Windows 7 64-bit
Version: 7 SP1 6.1.7601.24231
System architecture: Intel CPU Family:6, Model:13, Stepping:7 with MMX, SSE Integer, SSE FP, SSE2, SSE3, SSE4.1, SSE4.2, AVX, HyperThreading
Physical processor count: 6
Logical processor count: 12
Processor speed: 4044 MHz
Built-in memory: 65480 MB
Free memory: 60100 MB
Memory available to Photoshop: 60100 MB
Memory used by Photoshop: 100 %
Here is my present scratch disc set-up. C is not one of them:

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As i think its due to file size is your version is fully updated ? try that then check it...Thanks.
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It should be up to date as I frequently get notices to update the software through the CC App and I always do so. Says I am running version 19.16 and only options presently available are:
Open
View Tutorial
Manage/Uninstall
Manage/Other Versions.
I also cleaned up disc space on C: and now have 28.5 GB Free. Still will not open.
Is 64 GB of RAM too small?
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RAM is good can you share a file so i can see at my side it working for me or not...Thanks.
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sent you a pm.
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i replied back
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Hi
You really need to free up space on your C drive, 7GB is way to low, first thing you should try to do is free up space to see if that resolves the issue.
Take a look here
How Much Free Space Should You Leave on Your Windows PC?
Also you haven't mentioned what version of Photoshop you have
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Good article, but for the purposes here it omits one crucial element: The Photoshop scratch disk.
Photoshop moves vast amounts of data around, and RAM is never enough to hold it all. So Photoshop reserves a portion of your drive for temporary storage of working data, aka scratch disk. The scratch disk is Photoshop's "main memory", with RAM as a fast access cache. Very often, "not enough memory"-messages really refer to disk space.
How much space you need for the scratch disk depends on how big your files are (and how many are open at the same time). It could be anywhere from 80GB to a full TB.
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Me too. My photoshop cc 2017 show that pop up when I use brush size over 100px.
My pc is window 10pro, Ram4 Gb with i5 8th gen
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Hi
The issue you are having is most likely due to this
Error while accessing performance preferences - 'An integer between 96 and 8 is required.'
Which was fixed in version 19.1.5
You have 2 choices either update to version CC2018 19.1.6 or apply the fix in the article
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Unfortunately, I am running 19.1.6 and I had tried the fix anyway and it did not help.
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At the moment of the error, and while it is still on screen, check how much free space is on C. I wonder if the system paging files have filled up.
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"At the moment of the error, and while it is still on screen, check how much free space is on C. I wonder if the system paging files have filled up."
28.5 GB Free on C: drive before powering up PS and when the memory error occurs (and is left on screen).
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