Did this issue start happening after the update? Can you let us know the exact versions?
Also, is there more than one version of Photoshop installed on your system? Which image format are you working on?
"Edit In" will not work if the original files are unavailable to Lightroom. Where are the images located? Could you please try deselecting "Use Graphics Processor" in Lightroom's Preferences > Performance, then relaunch Lightroom and let us know if it helps?