It's with any workspace. With Photoshop open, if I minimize it to the system tray, audio is fine. As soon as I click on the icon to make it the active window, the audio stops. I assume that it must be due to Photoshop's ability to edit video which uses audio, but I never use it for that purpose. It's interesting, when Photoshop is open and I click to check the Windows audio settings, the audio starts playing again. As soon as I close the settings window, the audio stops.