Photoshop 22.4.3 upgrade stopped responding when opening PSD files, then Finder stopped responding. After multiple restarts, I had to reinstall 22.4.2, and am finally able to work.
MacBook Pro (16-inch, 2019)
2.3 GHz 8-Core Intel Core i9
32 GB 2667 MHz DDR4
AMD Radeon Pro 5500M 4 GB
Big Sir 11.4