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This process worked for me, hopefully it will work for other sufferin the same really annoying issue.
FYI, I am using Photoshop 22.4.2 on iMac Pro Big Sur 11.3.1
The Wacom Drivers need to be COMPLETELY uninstalled.
Follow the steps from:
I also deleted ANY file in the folders listed that had Wacom in the filename.
As a precaution I also used AppCleaner (https://freemacsoft.net/appcleaner/) to remove the 4 files from Applications > Wacom Tablet folder. (Lots more wacom related files detected)
I installed the previous version of the wacom driver (6.3.41-2) and restarted my computer.
After setting my tablet and pen preferences, also disabled all tablet button modifier keys. (does anyone use those!)
All working as it should in Photoshop for the past few hours, no more sticky ALT, CMD or SHIFT keys.
thank you for sharing this solution with the whole community 🙂