This problem start just today, i try open the Photoshop and all the window tools are gone. So open manually, but they don't fix, they stay "floating" and when i close and open the app again, all the windows close too.
Yes, you will lose customization if you reset prefererences. It's a best practice to save customization before you need it, though, otherwise you are at risk to lose them anyway. Back them up now, even if you don't reset preferences. In addition to these links, you can use the panel menu for each item to save action sets, styles, brushes, shapes, etc., so they can be loaded back in.