Wanted to add that, I can save and open my files. It's but cannot open a layer mask to edit it. It exists. Just can't open it with out the error messgae.
I've deselected the Graphics Processor and unchecked the Open CL. I've also chosen reset Preferences Upon Quit. I'm currently using Mac OS Catalina and CC 2021. They were playing reasonably well with each other up unitl today. Sadly, I uninstalled CC 2020.