Most Windows Wacom users found that they had to stop using WinTab Application interface with Photoshop 21.2.2 to get Pen pressure working with Photoshop 21.2.2. They had to switch to using Windows INK. When they Switch to Windows INK the Clone Stamp Brush tracking cross hair did not function with Windows INK. However they could use their Mouse and tracking did work. They also found the could not turn off Microsoft Pen Feedback cursors for Windows's setting doe not work. Which was one of the reasons they were using WinTab and not Windows INK. Other users complain the Windows INK added a lot more lag to brushes them when the were able to use WinTab. You are the first to report having mouse problems. I had to switch to a corded mouse a while back for Windows 10 was having major issues with My Microsoft Bluetooth mouse. I find the Logitech G502 is great for Photoshop. Zooming works great with the zoom tool and with the mouse wheel. Try resetting all tools and If the doe nor fix you mouse reset your Photoshop preferences.