Sorry to learn about Photoshop's blank workspace issue on macOS Big Sur. Would you mind telling us the version of Photoshop you're on?
Please go to the System Preferences of macOS, then Security and Privacy & select the Privacy tab. Once there, please select Accessibility from the list on the left and add Photoshop to the list by unlocking the window using the lock icon. Also, grant permissions to Photoshop under Full disk access. Once done, restart the computer and let us know if that helps.
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