Unfortunately I've been running into issues with Adobe Premiere for over a year now with my new PC. As soon as I use the hardware accelerated plugins from Red Giant - Universe, my adobe crashes or playback stops. And as I try to render the video it also crashes. I've contacted Red Giant/Maxon, but they can't reproduce the problem on their end.
I believe this is an issue between AMD and Premiere unfortunately.
Switching from video renderer to Software only instead of Hardware accelerated does seem to stabilize it and create fewer crashes however, having render times of over 10 hours is just no option for me.